Toxic interactions between lithium and non-steroidal anti-inflammatory drugs

Toxic interactions between lithium and non-steroidal anti-inflammatory drugs

Affective disorder and arthritis are both common conditions, and drugs form the mainstay of treatment for both illnesses. Despite the large variety of agents used to treat both disorders, toxic interactions between psychotropic and the anti-rheumatic drugs seem uncommon. One combination that has recently attracted some attention is lithium toxicity precipitated by certain non-steroidal anti-inf...

Toxic interactions between lithium and non-steroidal anti-inflammatory drugs.

Affective disorder and arthritis are both common conditions, and drugs form the mainstay of treatment for both illnesses. Despite the large variety of agents used to treat both disorders, toxic interactions between psychotropic and the anti-rheumatic drugs seem uncommon. One combination that has recently attracted some attention is lithium toxicity precipitated by certain non-steroidal anti-inf...

Toxic elevation of serum lithium concentration by non-steroidal anti-inflammatory drugs.

It is estimated that four million people in the United Kingdom have either osteo arthritis or rheumatoid arthritis. With the extension in lifespan seen in recent decades, the number is thought to be increasing. Many of the above will be treated with non-steroidal anti-inflammatory drugs. Lithium has been proven to be useful in the prophylaxis of affective disorders. It is also used in refractor...

Non-steroidal anti-inflammatory drugs.

Cross hepatotoxicity between non-steroidal anti-inflammatory drugs.

I Lyell A. The staphylococcal scalded skin syndrome in historical perspective: emergence of dermopathic strains of Staphylococcus aureus and discovery of the epidermolytic toxin. A review of events up to 1970. 7 Am AcadDermatol 1983;9;:285-94. 2 Melish ME, Glasgow LA. The staphylococcal scalded skin syndrome. Development of an experimental model. NEnglJMed 1970;282:1114-9. 3 Dowsett EG, Petts D...